Age-related loss of the beta subunit of soluble guanylyl cyclase impairs NO responsiveness, potentially contributing to enhanced intimal thickening following vascular injury in older individuals.
No takes yet. Share an insight, caveat, or question.
Age-related sGC-β loss may blunt NO vascular protection in elderly; hypothesis-generating for human restenosis mechanisms and therapies.
Chen et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: