Why the study?
Does propranolol alter atrial-specific granule number and plasma ANP levels in rats on varying sodium intakes?
Population
Rats on low and high sodium intakes
Comparison
Propranolol vs No propranolol / varying sodium diets
Design
Preclinical
Authors
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Propranolol effects on ANP-renin interplay vary by sodium intake in rats; hypothesis-generating and should not yet change clinical practice.
Does propranolol alter atrial-specific granule number and plasma ANP levels in rats on varying sodium intakes?
Dietary sodium intake is an important determinant of the response of atrial-specific granule number and plasma ANP levels to beta-adrenoceptor blockade with propranolol in rats.
Penner et al. (1990) studied this question.
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