Key result
Epicardial adipose tissue activity was independently correlated with increased 18F-fluorodeoxyglucose uptake in the atrium (B 1.39) and atrial appendage in patients with atrial fibrillation.
Why the study?
What factors are associated with increased atrial 18F-FDG uptake in patients with atrial fibrillation?
Observational (n=70)
Single-blind
No
What factors are associated with increased atrial 18F-FDG uptake in patients with atrial fibrillation?
Effect estimate: B 1.39 (95% CI 0.635-2.146)
p-value: p=<0.001
Increased epicardial adipose tissue activity is independently associated with enhanced atrial 18F-FDG uptake in patients with atrial fibrillation, suggesting a potential link between localized inflammation and AF.
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Supports epicardial fat activity as marker of atrial inflammation in AF; leaves open prognostic value and therapeutic targeting.
Xie et al. (2018) conducted an observational in Atrial fibrillation (n=70). 18F-fluorodeoxyglucose (FDG) PET/CT vs. Control subjects without history of AF or cardiovascular disease was evaluated on Linear correlation between epicardial adipose tissue activity (SUVmax of RCA) and atrial activity (B 1.39, 95% CI 0.635-2.146, p=<0.001). Epicardial adipose tissue activity was independently correlated with increased 18F-fluorodeoxyglucose uptake in the atrium (B 1.39) and atrial appendage in patients with atrial fibrillation.
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