Key result
High right atrial 18F-FDG uptake was an independent risk factor for stroke (HR 4.264) and improved stroke prediction when added to the CHA2DS2-VASc score in patients with atrial fibrillation.
Why the study?
Stroke is the most severe complication of AF, and investigators sought to determine whether atrial FDG uptake on PET/CT is linked to stroke and adds incremental predictive value to the CHA2DS2-VASc score.
Does high right atrial 18F-FDG uptake predict stroke in patients with atrial fibrillation?
Cohort (n=230)
No
Does high right atrial 18F-FDG uptake predict stroke in patients with atrial fibrillation?
Hazard Ratio: 4.264 (95% CI 1.368–13.293)
p-value: p=0.012
Right atrial 18F-FDG uptake is an independent predictor of stroke in patients with atrial fibrillation and provides incremental prognostic value over the standard CHA2DS2-VASc score.
No takes yet. Share an insight, caveat, or question.
May refine AF stroke risk stratification beyond CHA2DS2-VASc; hypothesis-generating and requires prospective validation.
Wang et al. (2022) conducted a cohort in Atrial Fibrillation (n=230). High right atrial 18F-FDG uptake (SUVmax ≥ 2.62) vs. Low right atrial 18F-FDG uptake (SUVmax < 2.62) was evaluated on Occurrence of stroke (HR 4.264, 95% CI 1.368-13.293, p=0.012). High right atrial 18F-FDG uptake was an independent risk factor for stroke (HR 4.264) and improved stroke prediction when added to the CHA2DS2-VASc score in patients with atrial fibrillation.
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