Key result
Obesity is linked to high cardiovascular risk via atherogenic plasma index in over ~90% of adults.
Why the study?
Identifying higher-risk patients with obesity is essential because providing treatment access to all individuals is unsustainable, motivating the evaluation of new risk stratification tools across obesity classes.
Cross-Sectional (n=404)
No
The study demonstrates a very high prevalence of cardiometabolic risk among adults with obesity, highlighting the utility of continuous metabolic severity scores and the atherogenic index of plasma for risk stratification.
Supports AIP screening in obese adults; leaves open whether risk stratification improves outcomes in prospective studies.
The epidemic of obesity worldwide has been recognized as a very important challenge. Within its complexity, the identification of higher-risk patients is essential, as it is unsustainable to offer access to treatment to all people with obesity. Several new approaches have recently been presented as important tools for risk stratification. In this research, we applied several of these tools in a cross-sectional study involving adults with obesity classes I, II, III, and super-obesity. The participants had their cardiometabolic risk profiles assessed. The study included adults with obesity aged 18 to 50 years (n = 404), who were evaluated using anthropometric, body composition, hemodynamic, physical fitness, and biochemical assessments. These variables were used to identify the prevalence of risk factors for cardiometabolic diseases according to the classes of obesity by gender and age group. The results showed high prevalence of risk factors, especially among the upper classes of obesity (BMI > 35 kg/m2) using single parameters as the waist circumference, with almost 90% above the cut-off point. For smaller numbers such as Glycated Hemoglobin, however, the prevalence was around 30%. Indexes such as the atherogenic index of plasma (AIP) had the highest prevalence, with 100% of the male participants identified as being at increased risk for cardiovascular disease.
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Westphal et al. (2023) conducted a cross-sectional in Obesity (n=404). Obesity (BMI ≥ 30 kg/m2) was evaluated on Prevalence of cardiometabolic risk factors. Among adults with obesity, cardiometabolic risk factors were highly prevalent, with 100% of men and 92.8% of women presenting an atherogenic index of plasma indicating moderate to high cardiovascular risk.
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