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May 1, 1995Journal of the American College of CardiologyOpen Access

Exercise capacity and incidence of myocardial perfusion defects after Kawasaki disease in children and adolescents

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Why the study?

Does coronary artery status affect exercise capacity and myocardial perfusion in children and adolescents after Kawasaki disease?

Population

46 children and adolescents with Kawasaki disease, classified by coronary artery status

Comparison

Exercise testing with monitoring of ECG changes… vs Comparison among groups based on coronary artery…

Design

Cross-sectional

Authors

SPStephen M. ParidonFGFrank M. GaliotoJVJulie Vincent

Discussion

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Overview

Normal exercise capacity may mask perfusion defects after Kawasaki disease; extends prior small reports but leaves open need for outcome data.

Structured PICO

Does coronary artery status affect exercise capacity and myocardial perfusion in children and adolescents after Kawasaki disease?

P
Population
46 children and adolescents with Kawasaki disease, classified by coronary artery status (no objective evidence of coronary artery lesions n=27, resolved aneurysms n=11, persistent coronary aneurysms n=8)
I
Intervention
Exercise testing with monitoring of ECG changes and oxygen consumption, and single-photon emission computed tomographic (SPECT) imaging using technetium-99m sestamibi at rest and during peak exercise
C
Comparator
Comparison among groups based on coronary artery status (no lesions vs. resolved aneurysms vs. persistent aneurysms)
O
Outcome
Maximal oxygen consumption and incidence of myocardial perfusion defectssurrogate

Stress-induced myocardial perfusion defects are common in children and adolescents after Kawasaki disease, even in those with normal exercise capacity and no persistent coronary abnormalities.

Cite This Study

Paridon et al. (1995) studied this question.

synapsesocial.com/papers/6a1c5201ea84844e355fbaa3https://doi.org/10.1016/0735-1097(95)00003-m
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pathological features of coronary arteries in children with Kawasaki disease in which coronary arterial aneurysm was absent at autopsy. Quantitative analysis.1988 · 103 citations
  2. 2Intravascular ultrasound of coronary arteries in children. Assessment of the wall morphology and the lumen after Kawasaki disease.1994 · 176 citations
  3. 3Kawasaki Disease: Cardiac Problems and Management1988 · 81 citations
  4. 4Kawasaki Disease: Cardiac Problems and Management1988 · 11 citations