Key result
Exercise tissue Doppler echocardiography identified coronary arterial stenosis in patients after Kawasaki syndrome with 75% sensitivity and 64% specificity using a peak diastolic velocity <90 mm/s.
Why the study?
Does exercise tissue Doppler and strain rate imaging detect regional myocardial dysfunction in asymptomatic patients with coronary arterial lesions after Kawasaki syndrome?
Population
17 asymptomatic patients with coronary arterial lesions after Kawasaki syndrome, and 17 age- and…
Comparison
Tissue Doppler echocardiography and strain rate… vs Age- and gender-matched control group
Design
Case-control
Authors
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May support noninvasive screening for coronary stenosis post-Kawasaki; leaves open prospective validation before clinical adoption.
Case-Control (n=34)
Does exercise tissue Doppler and strain rate imaging detect regional myocardial dysfunction in asymptomatic patients with coronary arterial lesions after Kawasaki syndrome?
p-value: p=<0.05
Exercise tissue Doppler echocardiography can detect early diastolic impairment in segments supplied by stenotic coronary arteries in children after Kawasaki syndrome before systolic dysfunction occurs.
Arnold et al. (2007) conducted a case-control in Kawasaki syndrome with coronary arterial lesions (n=34). Exercise tissue Doppler echocardiography and strain rate imaging vs. Age- and gender-matched controls was evaluated on Peak diastolic velocity during exercise in segments supplied by stenotic coronary arteries (p=<0.05). Exercise tissue Doppler echocardiography identified coronary arterial stenosis in patients after Kawasaki syndrome with 75% sensitivity and 64% specificity using a peak diastolic velocity <90 mm/s.
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