Key result
Speckle tracking echocardiography in 15 children with Kawasaki disease showed reduced left ventricular strain and strain rate during the acute phase that gradually improved with treatment.
Why the study?
Does treatment for Kawasaki disease improve myocardial mechanics measured by speckle tracking and tissue Doppler imaging in children?
Population
15 children with Kawasaki disease (KD) and 15 healthy children (controls), n=30
Comparison
Treatment for Kawasaki disease vs Healthy children and pre-treatment baseline
Design
Cohort
Follow-up
During treatment (exact duration not specified)
Authors
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Speckle tracking may aid monitoring of reversible LV impairment in acute Kawasaki disease; leaves open need for larger prospective validation before routine use.
Case-Control (n=30)
Does treatment for Kawasaki disease improve myocardial mechanics measured by speckle tracking and tissue Doppler imaging in children?
Speckle tracking echocardiography and tissue Doppler imaging demonstrate that left ventricular myocardial function is impaired during the acute phase of Kawasaki disease and gradually improves with treatment.
Azak et al. (2017) conducted a case-control in Kawasaki disease (n=30). Treatment for Kawasaki disease vs. Healthy children was evaluated on Myocardial deformation and function (strain, strain rate, and ejection time). Speckle tracking echocardiography in 15 children with Kawasaki disease showed reduced left ventricular strain and strain rate during the acute phase that gradually improved with treatment.