Key result
Two-dimensional speckle tracking echocardiography did not detect subclinical myocardial dysfunction in children with a history of Kawasaki disease compared to healthy controls at a mean follow-up of 3.55 years.
Why the study?
This study aimed to evaluate whether subclinical myocardial dysfunction could be detected by strain echocardiography during the late period in children with Kawasaki disease.
Does a history of Kawasaki disease cause subclinical myocardial dysfunction detected by strain echocardiography in long-term follow-up in children?
Population
30 patients with Kawasaki disease and 30 healthy age- and gender-matched children
Comparison
Patients with Kawasaki disease followed for at least 12 months vs healthy controls
Design
Case-control study
Follow-up
Mean 3.55±2.20 years
Authors
Loading...
Strain echocardiography detects no late subclinical dysfunction after Kawasaki disease; leaves open possible time-dependent LV changes in longer follow-up.
Case-Control (n=60)
Single-blind (outcome assessors)
No
Does a history of Kawasaki disease cause subclinical myocardial dysfunction detected by strain echocardiography in long-term follow-up in children?
Absolute Event Rate: -19.91% vs -20.12%
p-value: p=0.747
Long-term follow-up of children with Kawasaki disease showed no subclinical myocardial dysfunction using strain echocardiography compared to healthy controls, though strain values correlated with follow-up duration.
Kayabey et al. (2020) conducted a case-control in Kawasaki disease (n=60). History of Kawasaki disease vs. Healthy age- and gender-matched children was evaluated on Global longitudinal strain (GLS) (p=0.747). Two-dimensional speckle tracking echocardiography did not detect subclinical myocardial dysfunction in children with a history of Kawasaki disease compared to healthy controls at a mean follow-up of 3.55 years.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: