What does this research mean for the field?

During acute electrical stimulation of the canine heart, stimulation efficiency is maximized at an electrode radius of approximately 0.3 mm, and the specific non-linear relationships between electrode size and stimulation thresholds can be explained by modeling electrode impedance as an RC-series circuit. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 1, 1979Cardiovascular Research

Acute voltage, charge, and energy thresholds as functions of electrode size for electrical stimulation of the canine heart

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Why the study?

How does electrode size affect charge, voltage, and energy thresholds for electrical stimulation in canine hearts?

Population

Canine hearts in acute animal experiments

Comparison

Cathodal stimuli of 1 ms duration applied using… vs Different electrode sizes

Design

Preclinical

Authors

FLFred W. Lindemans AZA. N. E. ZIMMERMAN

Discussion

Member takes

Overview

Optimal radius ~0.3 mm minimizes energy in acute canine epicardium; hypothesis-generating for device design, requires human validation.

Structured PICO

How does electrode size affect charge, voltage, and energy thresholds for electrical stimulation in canine hearts?

Population

Canine hearts in acute animal experiments

Intervention

Cathodal stimuli of 1 ms duration applied using epicardial disc electrodes of varying sizes

Comparator

Different electrode sizes (radius varying from <0.2 mm to >1 mm)

Outcome

Charge, voltage, and energy thresholds for electrical stimulationsurrogate

In acute canine experiments, electrical stimulation is most efficient with an epicardial disc electrode radius of approximately 0.3 mm, where energy thresholds are minimized.

Cite This Study

Lindemans et al. (1979) studied this question.

synapsesocial.com/papers/6a1c73f8ecffbcc5fca15afc https://doi.org/10.1093/cvr/13.7.383

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July 1, 1979Cardiovascular Research

Acute voltage, charge, and energy thresholds as functions of electrode size for electrical stimulation of the canine heart

View Full Paper

Ask AI

Bookmark

Why the study?

How does electrode size affect charge, voltage, and energy thresholds for electrical stimulation in canine hearts?

Population

Canine hearts in acute animal experiments

Comparison

Cathodal stimuli of 1 ms duration applied using… vs Different electrode sizes

Design

Preclinical

Authors

FLFred W. Lindemans AZA. N. E. ZIMMERMAN

Discussion

Member takes

Overview

Optimal radius ~0.3 mm minimizes energy in acute canine epicardium; hypothesis-generating for device design, requires human validation.

Structured PICO

How does electrode size affect charge, voltage, and energy thresholds for electrical stimulation in canine hearts?

Population

Canine hearts in acute animal experiments

Intervention

Cathodal stimuli of 1 ms duration applied using epicardial disc electrodes of varying sizes

Comparator

Different electrode sizes (radius varying from <0.2 mm to >1 mm)

Outcome

Charge, voltage, and energy thresholds for electrical stimulationsurrogate

In acute canine experiments, electrical stimulation is most efficient with an epicardial disc electrode radius of approximately 0.3 mm, where energy thresholds are minimized.

Cite This Study

Lindemans et al. (1979) studied this question.

synapsesocial.com/papers/6a1c73f8ecffbcc5fca15afc https://doi.org/10.1093/cvr/13.7.383

View Full Paper

Ask AI

Bookmark