Why the study?
Does electrode size affect the electric potential distribution in cardiac tissue during electrical stimulation?
Population
Three-dimensional slab of cardiac tissue (computational bidomain model)
Comparison
Electrical stimulation with varying electrode… vs Different electrode sizes
Design
Preclinical
Authors
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Electrode edge effects warrant consideration in experimental stimulation; leaves open human translation and clinical validation.
Does electrode size affect the electric potential distribution in cardiac tissue during electrical stimulation?
Computational modeling demonstrates that during electrical stimulation of cardiac tissue, depolarization is strongest at the electrode edge and the ratio of peak depolarization to hyperpolarization remains close to three across a broad range of electrode sizes.
Patel et al. (2000) studied this question.
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