Key result
Acoustic quantification and color kinesis identify global and regional diastolic dysfunction, including delayed and heterogeneous endocardial motion, in patients with hypertensive heart disease.
Why the study?
Do acoustic quantification and color kinesis improve the assessment of left ventricular diastolic function in patients with hypertensive heart disease compared to traditional Doppler echocardiography?
Do acoustic quantification and color kinesis improve the assessment of left ventricular diastolic function in patients with hypertensive heart disease compared to traditional Doppler echocardiography?
Automated border detection techniques like acoustic quantification and color kinesis provide a more sensitive evaluation of diastolic dysfunction in hypertensive heart disease than traditional Doppler echocardiography.
May aid regional diastolic assessment in hypertensive heart disease; leaves open whether these techniques outperform Doppler in practice.
Acoustic quantification (AQ) and color kinesis (CK) are techniques that involve automated detection and tracking of endocardial borders. These methods are useful for the evaluation of global and regional left ventricular (LV) systolic function and more recently have been applied to evaluating LV diastolic performance. Assessment of diastolic dysfunction in hypertensive heart disease is a relevant clinical issue in which these techniques have proven useful. The diastolic portion of left atrium and LV AQ area waveforms are frequently abnormal in patients with left ventricular hypertrophy (LVH). Left ventricular AQ curves consistently demonstrate reduced rapid filling fraction (RFF) and peak rapid filling rate (PRFR), elevated atrial filling fraction (AFF), peak atrial filling rate (PAFR), and reductions in the ratio PRFR/PAFR. Acoustic quantification complements traditional Doppler echocardiographic evaluation of global diastolic function. Many patients with significant LVH and normal Doppler diastolic parameters can be identified as having diastolic dysfunction with AQ. In addition, CK has allowed the evaluation of regional diastolic performance in hypertensive patients. Regional filling curves obtained from CK have demonstrated that endocardial diastolic motion is commonly delayed and heterogeneous in patients with LVH.
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Spencer et al. (2003) conducted a review in Hypertensive heart disease. Acoustic quantification and color kinesis vs. Traditional Doppler echocardiography was evaluated on Global and regional left ventricular diastolic function. Acoustic quantification and color kinesis identify global and regional diastolic dysfunction, including delayed and heterogeneous endocardial motion, in patients with hypertensive heart disease.
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