Why the study?
What are the age-adjusted reference ranges for creatinine clearance in older women, and is the Cockcroft-Gault formula valid in this population?
Population
279 women, ages 40-95 years, housed in a metabolic research unit and consuming a meat-free diet.
Design
Cross-sectional
Authors
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May inform age-adjusted creatinine clearance norms in older women; supports Cockcroft-Gault factor but leaves open dosing impact.
What are the age-adjusted reference ranges for creatinine clearance in older women, and is the Cockcroft-Gault formula valid in this population?
This study establishes age-adjusted creatinine clearance reference values for older women and validates the 15% correction factor for women in the Cockcroft-Gault formula.
Sokoll et al. (1994) studied this question.
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