Why the study?
Does nifedipine alone or in combination with a beta-blocker improve exercise tolerance in patients with stable angina pectoris?
Population
21 patients with stable angina pectoris previously treated with beta-blockers, mean age 60.3 years
Comparison
Nifedipine 10 mg 3 times daily alone, and in… vs Placebo, and the patient's usual beta-blocker…
Design
RCT, randomized, double-blind
Follow-up
3-week periods
Authors
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Supports nifedipine for stable angina exercise tolerance; extends evidence for additive beta-blocker benefit.
Does nifedipine alone or in combination with a beta-blocker improve exercise tolerance in patients with stable angina pectoris?
Nifedipine improves exercise tolerance in patients with stable angina, with additive benefits when combined with a beta-blocker.
Ekelund et al. (1979) studied this question.