March 1, 1986HeartOpen Access

Treatment of angina pectoris with nifedipine and atenolol: efficacy and effect on cardiac function.

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Why the study?

Does nifedipine and atenolol singly or in combination improve exercise capacity and reduce ischemia in patients with angina pectoris?

Population

16 patients with angina pectoris

Comparison

Nifedipine 20 mg three times a day and atenolol… vs Placebo

Authors

IFIain FindlayRoyal Alexandra Hospital KMK. J. MacLeodNational Health Service MFMartin E. FordBinghamton University

Discussion

Member takes

Implication

Supports greater ischemia reduction with nifedipine-atenolol combination in angina; hypothesis-generating and should not yet change practice.

Structured PICO

Does nifedipine and atenolol singly or in combination improve exercise capacity and reduce ischemia in patients with angina pectoris?

Population

16 patients with angina pectoris

Intervention

Nifedipine 20 mg three times a day and atenolol 100 mg once a day singly and in combination

Comparator

Placebo

Outcome

Amount of work that could be done before angina and ST depression appearedsurrogate

The combination of nifedipine and atenolol is more effective than either agent alone in reducing exercise-induced ischemia in patients with angina pectoris.

Cite This Study

Findlay et al. (1986) studied this question.

synapsesocial.com/papers/6a701e97f44fa9f079dda948 https://doi.org/10.1136/hrt.55.3.240

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Implication

Supports greater ischemia reduction with nifedipine-atenolol combination in angina; hypothesis-generating and should not yet change practice.

Treatment of angina pectoris with nifedipine and atenolol: efficacy and effect on cardiac function.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Treatment of angina pectoris with nifedipine and atenolol: efficacy and effect on cardiac function.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider