Why the study?
Snoring correlates with carotid stenosis, raising the hypothesis that snoring after carotid artery stenting may promote or worsen clinical performance.
Does simulated snoring alter the hemodynamic environment in a patient-specific carotid artery model after stent implantation?
Does simulated snoring alter the hemodynamic environment in a patient-specific carotid artery model after stent implantation?
High-amplitude snoring significantly alters the local hemodynamic environment in stented carotid arteries, potentially increasing the risk of downstream vascular remodeling and thrombosis.
May warrant caution in stented carotid patients; hypothesis-generating for downstream thrombosis risk, needing human validation.
Snoring is common in overweight and elderly patients treated by endovascular stenting. Studies have proved a correlation between snoring and carotid stenosis, thus, snoring after carotid artery stenting (CAS) might promote or worsen clinical performance. This study tested this hypothesis by constructing a patient-specific carotid bifurcation model and numerically analyzing hemodynamic changes of the carotid artery under different snoring conditions. These conditions included small and large amplitude, low and high frequency, and different age groups. The results found that high amplitude snoring suppressed the disturbed flow at the stented segment while the downstream region of ICA became more chaotic, accounting for in-stent intimal restenosis and thrombosis. Furthermore, local blood flow patterns of elder groups with snoring symptoms were more likely to be changed due to low-speed flow, increasing the possibility of vascular remodeling and thrombosis. Besides, increased snoring frequency hardly influenced the local disturbed flow. Therefore, older adults should receive medical treatment actively after stenting for high-amplitude snoring as soon as possible to avoid potential adverse events.
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Zhang et al. (2023) studied this question.
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