Why the study?
Does aortic valve replacement improve survival and functional status in patients with severe left ventricular dysfunction and aortic stenosis or regurgitation?
Does aortic valve replacement improve survival and functional status in patients with severe left ventricular dysfunction and aortic stenosis or regurgitation?
Aortic valve replacement in patients with severe left ventricular dysfunction (EF <30%) and aortic stenosis or regurgitation is associated with acceptable long-term survival and significant improvements in functional status and ejection fraction.
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May support AVR consideration in severe LV dysfunction with AS/AR; leaves open randomized confirmation of benefit.
Rothenburger et al. (2003) studied this question.
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