Key result
Cardiac CT, PET, and hybrid PET/CT emerge as powerful noninvasive tools for comprehensive CAD evaluation.
Why the study?
Cardiac CT and PET are emerging noninvasive imaging tools for evaluating atherosclerosis in patients with known or suspected CAD, with potential advantages over invasive angiography and conventional SPECT imaging.
Cardiac CT and PET, including hybrid PET/CT, are emerging as powerful tools for the comprehensive noninvasive evaluation of anatomy and function in patients with ischemic heart disease.
CTA and PET may refine noninvasive CAD plaque assessment; leaves open routine adoption pending prospective validation.
C ardiac computed tomography (CT) and positron emis- sion tomography (PET) are emerging as powerful noninvasive imaging tools for the evaluation of atherosclerosis in patients with known or suspected coronary artery disease (CAD).Unlike invasive coronary angiography, CT coronary angiography (CTA) not only assesses disease within the coronary lumen but can also provide direct qualitative and quantitative information about nonobstructive atherosclerotic plaque burden within the vessel wall.Thus, it is possible that CTA-based patient evaluation may provide more clinically relevant information on which to base risk assessments compared with conventional "lumenography."On the other hand, PET is rapidly growing as a powerful and efficient alternative to conventional single-photon emission CT (SPECT) imaging to evaluate regional myocardial perfusion and metabolism in patients with CAD.In addition, PET scanners are now being converted to hybrid PET/CT devices, which, in the setting of CAD, offer the potential for a comprehensive noninvasive cardiac evaluation of anatomy and function.This review will discuss current and potential future applications of cardiovascular CT, PET, and hybrid PET/CT, with a particular focus on ischemic heart disease.
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Carli et al. (2007) conducted a review in Coronary artery disease (CAD). Cardiac computed tomography (CT), positron emission tomography (PET), and hybrid PET/CT vs. Invasive coronary angiography and conventional SPECT was evaluated. Cardiac CT, PET, and hybrid PET/CT are emerging as powerful noninvasive imaging tools for the comprehensive evaluation of anatomy, function, and atherosclerosis in patients with coronary artery disease.
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