Population
Heart samples (n = 9) collected from five swine at six weeks post-infarction
Comparison
Ex vivo MRI using late gadolinium-enhancement… vs Whole-mount histology
Design
Preclinical
Follow-up
6 weeks post-infarction
Authors
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Validates MRI scar metrics in swine infarct models; hypothesis-generating for human post-MI imaging, no practice change yet.
Ex vivo high-resolution LGE and DWI MRI accurately quantify dense scar and heterogeneous border zone fibrosis in infarcted swine hearts, correlating strongly with histology.
Pop et al. (2013) studied this question.
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