What does this research mean for the field?

Porcine heart-valve replacement results in an 80% eight-year survival rate with low operative mortality (3%) and primary valve dysfunction (4%), demonstrating its long-term clinical viability despite some risk of thromboembolism. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 29, 1981New England Journal of Medicine

Five to Eight-Year Follow-up of Patients Undergoing Porcine Heart-Valve Replacement

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Population

n=128 patients undergoing porcine heart-valve replacement

Design

Cohort

Follow-up

five to eight years

Authors

LCLawrence H. CohnInterventional / Structural Cardiology GMGilbert H. MudgeHeart Failure / Cardiomyopathy FPFrederick E. PratterEastern Oregon University

Discussion

Member takes

Implication

May aid counseling on expected valve-replacement longevity; leaves open validation against contemporary prostheses in randomized cohorts.

Structured PICO

Population

n=128 patients undergoing porcine heart-valve replacement (47 aortic-valve replacement, 62 mitral-valve replacement, and 19 combined aortic-valve and mitral-valve replacement)

Intervention

Porcine heart-valve replacement (aortic, mitral, or combined)

Outcome

Actuarial probability of survival at eight yearshard clinical

Porcine heart-valve replacement demonstrates an 80% actuarial survival at eight years, though thromboembolic events and valve dysfunction remain notable long-term risks.

Cite This Study

Cohn et al. (1981) studied this question.

synapsesocial.com/papers/6a1d1c401c2cbcb15c5dc754 https://doi.org/10.1056/nejm198101293040503

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January 29, 1981New England Journal of Medicine

Five to Eight-Year Follow-up of Patients Undergoing Porcine Heart-Valve Replacement

View Full Paper

Ask AI

Bookmark

Population

n=128 patients undergoing porcine heart-valve replacement

Design

Cohort

Follow-up

five to eight years

Authors

LCLawrence H. CohnInterventional / Structural Cardiology GMGilbert H. MudgeHeart Failure / Cardiomyopathy FPFrederick E. PratterEastern Oregon University

Discussion

Member takes

Implication

May aid counseling on expected valve-replacement longevity; leaves open validation against contemporary prostheses in randomized cohorts.

Structured PICO

Population

n=128 patients undergoing porcine heart-valve replacement (47 aortic-valve replacement, 62 mitral-valve replacement, and 19 combined aortic-valve and mitral-valve replacement)

Intervention

Porcine heart-valve replacement (aortic, mitral, or combined)

Outcome

Actuarial probability of survival at eight yearshard clinical

Porcine heart-valve replacement demonstrates an 80% actuarial survival at eight years, though thromboembolic events and valve dysfunction remain notable long-term risks.

Cite This Study

Cohn et al. (1981) studied this question.

synapsesocial.com/papers/6a1d1c401c2cbcb15c5dc754 https://doi.org/10.1056/nejm198101293040503

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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