Key result
Bioprosthetic valve replacement in patients over 65 shows ~79% five-year survival and low structural deterioration.
Why the study?
Mid-term outcomes and complications after bioprosthetic valve replacement in elderly patients were not well characterized.
Design
Observational cohort study
Follow-up
Mean 75 months (range 2 months to 12 years)
Authors
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Supports bioprosthetic valves in patients >65; extends observational data but leaves open randomized comparisons with mechanical valves.
Observational (n=110)
Bioprosthetic valve replacement in elderly patients (>65 years) provides acceptable mid-term survival with low rates of structural valve deterioration and reoperation mortality.
Helft et al. (1995) conducted an observational in Valvular heart disease requiring replacement (n=110). Bioprosthetic valve replacement was evaluated on Actuarial patient survival at 5 years. Bioprosthetic valve replacement in patients over 65 years old demonstrated a 5-year survival of 79.4% and a low rate of primary structural deterioration (0.9% per patient-year).
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