Why the study?
Does cyclooxygenase inhibition affect renal hemodynamics differently based on sex, ovarian status, and surgical stress in rats?
Does cyclooxygenase inhibition affect renal hemodynamics differently based on sex, ovarian status, and surgical stress in rats?
There is a functional sex difference in baseline renal hemodynamics and the renal response to cyclooxygenase inhibition, which is unveiled by surgical stress in female rats.
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Sex- and anesthesia-dependent COX effects on rat renal hemodynamics; leaves open relevance to human patients or practice.
Munger et al. (1988) studied this question.
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