What does this research mean for the field?

Oxidative stress and redox imbalance in perivascular adipose tissue (PVAT) is a key pathophysiological mechanism driving obesity-induced cardiovascular diseases, making it a potential target for pharmacological intervention. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 10, 2023AntioxidantsOpen Access

Perivascular Adipose Tissue Oxidative Stress in Obesity

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Why the study?

In obesity, perivascular adipose tissue becomes dysfunctional, making its redox balance a potential pathophysiological mechanism underlying obesity-induced cardiovascular diseases.

Design

Review

Authors

AMAndy W. C. ManVascular / Pulmonary Vascular YZYawen ZhouYantai University NXNing XiaVascular Medicine

Discussion

Member takes

Implication

PVAT oxidative stress may underlie obesity-related CVD; leaves open targeted antioxidant trials before any practice change.

Structured PICO

Population

Obesity (context for perivascular adipose tissue oxidative stress)

Intervention

Potential pharmacological intervention of PVAT oxidative stress

This review highlights the role of perivascular adipose tissue oxidative stress as a potential pathophysiological mechanism underlying obesity-induced cardiovascular diseases.

Cite This Study

Man et al. (2023) studied this question.

synapsesocial.com/papers/6a1d2fc75b7fddc35204f40c https://doi.org/10.3390/antiox12081595

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Perivascular Adipose Tissue Oxidative Stress in Obesity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Perivascular Adipose Tissue Oxidative Stress in Obesity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider