Population
Isolated arterioles (40-80 micron diameter) from the hamster cheek pouch
Comparison
Application of alpha-adrenoceptor agonists and… vs Luminal versus adventitial application
Design
Preclinical
Authors
Loading...
Endothelial barrier may modulate arteriolar responses to hydrophilic agents; leaves open translation to human microvascular function.
The endothelial cell layer in arterioles acts as a diffusion barrier to small, water-soluble molecules, which significantly modulates arteriolar reactivity to vasoactive substances.
Lew et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: