June 1, 2001Hypertension
Relation of Age to Left Ventricular Function and Systemic Hemodynamics in Uncomplicated Mild Hypertension
Population
272 asymptomatic, unmedicated adults (25 to 80 years old) with uncomplicated essential hypertension
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports compensatory hemodynamics in aging hypertension; hypothesis-generating and requires prospective validation.
Structured PICO
P
Population
272 asymptomatic, unmedicated adults (25 to 80 years old) with uncomplicated essential hypertension
O
Outcome
Left ventricular dimensions, endocardial and midwall left ventricular shortening, stroke index and cardiac index, end-systolic stress, and vascular stiffness measures (pulse pressure/stroke index and beta)surrogate
In uncomplicated mild hypertension, aging is associated with progressively increased vascular stiffness but preserved cardiac index and peripheral resistance due to compensatory geometric and functional changes.
Cite This Study
Slotwiner et al. (2001) studied this question.