Why the study?
How does aging affect endothelial function, carotid intima-media thickness, blood pressure, and echocardiographic measurements in normotensive healthy subjects?
Population
Healthy normotensive subjects divided into three age groups: young adults, middle age, and elderly.
Design
Cross-sectional
Authors
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Age-related CV remodeling occurs even in healthy normotensives; leaves open whether these changes warrant intervention or predict outcomes.
How does aging affect endothelial function, carotid intima-media thickness, blood pressure, and echocardiographic measurements in normotensive healthy subjects?
Aging is associated with progressive structural and functional cardiovascular changes, including increased blood pressure, left ventricular mass, and carotid IMT, and decreased LVEF and diastolic function, even in healthy normotensive individuals.
Lin et al. (2014) studied this question.
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