Population
66 healthy subjects of different ages (20-82 years)
Design
Cross-sectional
Authors
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May reflect age-related endothelial dysfunction; hypothesis-generating and requires longitudinal validation before clinical use.
Aging is associated with progressive brachial artery endothelial dysfunction, which correlates with increased carotid intima-media thickness and precedes changes in left ventricular geometry.
Djurić et al. (1999) studied this question.
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