Why the study?
Does ultrasound tissue characterization detect myocardial ultrastructural changes related to collagen content in patients with chronic kidney disease compared to uncomplicated hypertensive controls?
Population
60 subjects: 25 hemodialysis patients, 25 patients with moderate to severe chronic renal failure, and 10…
Comparison
Ultrasound tissue characterization vs Uncomplicated essential hypertension patients…
Design
Cross-sectional
Authors
Loading...
May identify progressive myocardial changes in CKD; hypothesis-generating and should not yet change practice.
Does ultrasound tissue characterization detect myocardial ultrastructural changes related to collagen content in patients with chronic kidney disease compared to uncomplicated hypertensive controls?
Acoustic densitometry can detect early myocardial tissue changes, likely reflecting interstitial collagen deposition, which progressively worsen across the spectrum of chronic kidney disease.
Salvetti et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: