Key result
Myocardial fibrosis, estimated by integrated backscatter, was an independent determinant of diastolic dysfunction in patients on chronic haemodialysis (OR 1.212; P=0.040).
Why the study?
Is myocardial fibrosis associated with left ventricular diastolic dysfunction in patients with ESRD on chronic haemodialysis?
Population
25 patients with end-stage renal disease (ESRD) undergoing chronic haemodialysis
Design
Cross-sectional
Authors
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May aid risk stratification in hemodialysis diastolic dysfunction; leaves open causal role and need for prospective trials.
Observational (n=25)
Is myocardial fibrosis associated with left ventricular diastolic dysfunction in patients with ESRD on chronic haemodialysis?
Odds Ratio: 1.212
p-value: p=0.040
In patients with ESRD on hemodialysis, myocardial fibrosis estimated by ultrasound integrated backscatter is independently associated with left ventricular diastolic dysfunction.
Losi et al. (2010) conducted an observational in End-stage renal disease undergoing haemodialysis (n=25). Myocardial fibrosis (integrated backscatter) vs. Lower integrated backscatter was evaluated on Diastolic dysfunction (OR 1.212, p=0.040). Myocardial fibrosis, estimated by integrated backscatter, was an independent determinant of diastolic dysfunction in patients on chronic haemodialysis (OR 1.212; P=0.040).
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