Key result
An invasive strategy for nonagenarians with acute coronary syndrome was associated with reduced in-hospital all-cause mortality compared to a conservative strategy (12.0% vs 25.1%; P=0.001).
Why the study?
Does an invasive strategy reduce in-hospital all-cause mortality in elderly patients hospitalized with acute coronary syndrome?
Population
4,569 consecutive patients hospitalized with acute coronary syndrome at 24 Canadian hospitals, including…
Comparison
Invasive strategy vs Conservative strategy
Design
Cohort
Follow-up
in-hospital
Authors
Loading...
May support invasive strategy in nonagenarians with ACS despite higher bleeding; leaves open confirmation by randomized trials.
Observational (n=4,569)
Yes
Does an invasive strategy reduce in-hospital all-cause mortality in elderly patients hospitalized with acute coronary syndrome?
Absolute Event Rate: 12% vs 25.1%
p-value: p=0.001
An invasive strategy in elderly patients, including nonagenarians, presenting with ACS is associated with lower in-hospital mortality but higher bleeding risk.
Couture et al. (2018) conducted an observational in Acute coronary syndrome (n=4,569). Invasive strategy vs. Conservative strategy was evaluated on In-hospital all-cause mortality in nonagenarians (p=0.001). An invasive strategy for nonagenarians with acute coronary syndrome was associated with reduced in-hospital all-cause mortality compared to a conservative strategy (12.0% vs 25.1%; P=0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: