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January 1, 2011North American Journal of Medicine and ScienceOpen Access

Molecular and Pathophysiological Features of Angiotensinogen: A Mini Review

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Key result

This review highlights contemporary insights into the molecular characteristics and newly recognized pathophysiological functions of angiotensinogen beyond blood pressure regulation.

Design

Review

Authors

CWCongqing WuUniversity of KentuckyHLHong LüVascular / Pulmonary VascularLCLisa A. CassisVascular Medicine

Discussion

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Implication

Angiotensinogen's roles in atherosclerosis and obesity merit targeted study; leaves open any therapeutic implications beyond renin-angiotensin modulation.

PICO

P
Population
Angiotensinogen pathophysiology
I
Intervention / Comparator
Angiotensinogen

This review summarizes contemporary insights into the molecular characteristics and novel pathophysiological functions of angiotensinogen, such as its involvement in atherosclerosis and obesity.

Cite This Study

Wu et al. (2011) conducted a review in Angiotensinogen pathophysiology. Angiotensinogen was evaluated. This review highlights contemporary insights into the molecular characteristics and newly recognized pathophysiological functions of angiotensinogen beyond blood pressure regulation.

synapsesocial.com/papers/6a1d55597328fa9a742f579chttps://doi.org/10.7156/v4i4p183
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Bilateral Nephrectomy on Active Renin, Angiotensinogen, and Renin Glycoforms in Plasma and Myocardium1997 · 81 citations
  2. 2Role of N-Glycosylation in Human Angiotensinogen1998 · 43 citations
  3. 3Human Adipose Tissue Expresses Angiotensinogen and Enzymes Required for Its Conversion to Angiotensin II11998 · 321 citations
  4. 4Genetic Evidence That Lethality in Angiotensinogen-deficient Mice Is Due to Loss of Systemic but Not Renal Angiotensinogen2001 · 23 citations
  5. 5Reduced growth, abnormal kidney structure, and type 2 (AT 2 ) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT 1A and AT 1B receptors for angiotensin II1998 · 318 citations