Why the study?
Angiotensinogen had previously been assumed to be a passive substrate, but its inherent conformational mechanisms critical to angiotensin peptide cleavage, release, and blood pressure control required elucidation.
Design
Review
Authors
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May identify redox-sensitive targets for hypertension; leaves open whether these insights yield clinical therapies.
Key points are not available for this paper at this time.
Shu et al. (2021) studied this question.
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