Why the study?
Does a greater rate of decline in FEV1 predict increased total mortality in Japanese-American men?
Population
4,000 Japanese-American men initially aged 45-68 years, free of cardiovascular disease and cancer, with…
Comparison
Greatest rate of decline in FEV1 vs Smallest change in FEV1 (mean, +9 ml/year)
Design
Cohort
Follow-up
17 years
Authors
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Rapid FEV1 decline may flag higher mortality risk in Japanese-American men; hypothesis-generating and should not yet change practice.
Does a greater rate of decline in FEV1 predict increased total mortality in Japanese-American men?
A rapid decline in FEV1 is a significant predictor of long-term total mortality, particularly among past and current smokers.
Rodríguez et al. (1994) studied this question.
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