Why the study?
How do autonomic reflexes influence cardiovascular responses to isoprenaline infusions versus bolus injections in healthy volunteers?
Population
9 healthy volunteers
Comparison
Isoprenaline infusions and bolus injections… vs Isoprenaline infusions and bolus injections…
Design
Other
Authors
Loading...
Bolus isoprenaline after blockade may better isolate beta-adrenoceptor effects on listed parameters; leaves open validation for clinical sensitivity testing.
How do autonomic reflexes influence cardiovascular responses to isoprenaline infusions versus bolus injections in healthy volunteers?
Pre-ejection period, left ventricular diameter in systole, mean posterior wall velocity, and ventricular circumferential fibre shortening are useful parameters to evaluate cardiac beta-adrenoceptor sensitivity in vivo.
Martinsson et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: