Key result
Hepatic MRI demonstrated a significantly better correlation with microscopic fat content on biopsy than ultrasound (r=0.77 vs r=0.41, P<0.001).
Why the study?
Does MRI provide better correlation with liver biopsy for quantifying hepatic steatosis compared to ultrasound in patients with liver disease?
Population
38 patients undergoing hepatic biopsy for a variety of liver diseases
Comparison
Hepatic MRI through chemical shift imaging vs Ultrasound through echogenicity (n=31)
Design
Cross-sectional
Authors
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MRI may better quantify steatosis versus ultrasound in liver disease; leaves open need for prospective outcome studies before practice change.
Observational (n=38)
Does MRI provide better correlation with liver biopsy for quantifying hepatic steatosis compared to ultrasound in patients with liver disease?
Effect estimate: r = 0.77
p-value: p=<0.001
MRI is superior to ultrasound in detecting and quantifying minor degrees of fatty metamorphosis in the liver, though both are useful for identifying heavy fat accumulation.
Fishbein et al. (2005) conducted an observational in Hepatic steatosis (n=38). Hepatic MRI (chemical shift imaging) vs. Ultrasound was evaluated on Correlation with microscopic fat content on liver biopsy (r = 0.77, p=<0.001). Hepatic MRI demonstrated a significantly better correlation with microscopic fat content on biopsy than ultrasound (r=0.77 vs r=0.41, P<0.001).
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