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October 31, 2021International Journal of Environmental Research and Public HealthOpen Access

Identification of a High-Risk Group of New-Onset Cardiovascular Disease in Occupational Drivers by Analyzing Heart Rate Variability

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Key result

Lower standard deviation of NN intervals (SDNN) was associated with an increased 8-year risk of cardiovascular disease in occupational bus drivers (HR 1.87; 95% CI 1.11-3.13).

Why the study?

This study evaluated the effectiveness of noninvasive heart rate variability analysis to assess the risk of cardiovascular disease over a period of 8 years.

Does heart rate variability analysis predict the risk of new-onset cardiovascular disease in occupational drivers?

Population

161 drivers with CVD and 627 without from the Taiwan Bus Driver Cohort Study

Comparison

Lower vs higher HRV indices including median split for SDNN

Design

Cohort study

Follow-up

8 years

Authors

YWYing-Chuan WangCWChung‐Ching WangYYYa-Hsin Yao

Discussion

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Overview

May support HRV monitoring for risk stratification in drivers; leaves open whether targeting SDNN improves outcomes.

Study Design

Type

Cohort (n=788)

Structured PICO

Does heart rate variability analysis predict the risk of new-onset cardiovascular disease in occupational drivers?

P
Population
788 occupational drivers from the Taiwan Bus Driver Cohort Study (TBDCS) (161 with cardiovascular disease and 627 without)
I
Intervention
Heart rate variability (HRV) analysis (including SDNN, LF, RMSSD, HF)
C
Comparator
Higher vs lower levels of HRV parameters (e.g., median split for SDNN)
O
Outcome
New-onset cardiovascular disease (CVD) over 8 yearshard clinical

Main Result

Effect estimate: HR 1.87 (95% CI 1.11-3.13)

Lower standard deviation of NN intervals (SDNN) and low-frequency (LF) levels are associated with an increased 8-year risk of cardiovascular disease, particularly hypertensive disease, in occupational drivers.

Cite This Study

Wang et al. (2021) conducted a cohort in Cardiovascular disease (n=788). Heart rate variability (HRV) analysis (SDNN index) vs. Higher SDNN (median split) was evaluated on New-onset cardiovascular disease (HR 1.87, 95% CI 1.11-3.13). Lower standard deviation of NN intervals (SDNN) was associated with an increased 8-year risk of cardiovascular disease in occupational bus drivers (HR 1.87; 95% CI 1.11-3.13).

synapsesocial.com/papers/6a1d70b633e2df9c962f8530https://doi.org/10.3390/ijerph182111486
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heart rate variability in long‐term risk assessment in middle‐aged women with coronary heart disease: The Stockholm Female Coronary Risk Study2003 · 60 citations
  2. 2Novel Measures of Heart Rate Variability Predict Cardiovascular Mortality in Older Adults Independent of Traditional Cardiovascular Risk Factors: The Cardiovascular Health Study (CHS)2008 · 102 citations
  3. 3Heart rate variability and first cardiovascular event in populations without known cardiovascular disease: meta-analysis and dose–response meta-regression2013 · 522 citations
  4. 4Heart Rate Variability from Short Electrocardiographic Recordings Predicts Mortality from All Causes in Middle-aged and Elderly Men: The Zutphen Study1997 · 507 citations
  5. 5Reduced vagal cardiac control variancein exhausted and high strain job subjects2010 · 54 citations