December 1, 1987Annals of Neurology
Somatic and autonomic function in progressive autonomic failure and multiple system atrophy
Why the study?
What are the differences in somatic and autonomic function between patients with progressive autonomic failure and multiple system atrophy?
Population
62 consecutive patients with progressive autonomic failure or multiple system atrophy, mean age 67 vs 66…
Comparison
Assessment of somatic and autonomic function… vs Comparison between patients with progressive…
Design
Cross-sectional
Authors
Discussion
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Implication
Structured PICO
What are the differences in somatic and autonomic function between patients with progressive autonomic failure and multiple system atrophy?
P
Population
62 consecutive patients with progressive autonomic failure (PAF) (n=26) or multiple system atrophy (MSA) (n=36), mean age 67 (PAF) vs 66 (MSA) years.
I
Intervention
Assessment of somatic and autonomic function using quantitative sudomotor axon reflex test, plasma norepinephrine, thermoregulatory sweat test, heart rate responses to deep breathing and Valsalva maneuver, and blood pressure recordings.
C
Comparator
Comparison between patients with progressive autonomic failure (PAF) and multiple system atrophy (MSA).
O
Outcome
Extent and severity of autonomic failure, including postganglionic sudomotor and vasomotor functions, and plasma norepinephrine levels.surrogate
Cite This Study
Cohen et al. (1987) studied this question.