Why the study?
Which serum marker is the most sensitive for detecting acute myocardial infarction during the first hours after onset of chest pain?
Population
37 consecutive patients with acute myocardial infarction admitted to the coronary care unit within 4 hours…
Comparison
Measurement of serum markers: myoglobin, CKMB… vs Creatine kinase (CK) and CKMB activity
Design
Cohort
Follow-up
10 hours after admission
Authors
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Supports preferring mass assays, isoforms, myoglobin, and troponins over activity assays for early detection; extends comparisons yet remains hypothesis-generating.
Which serum marker is the most sensitive for detecting acute myocardial infarction during the first hours after onset of chest pain?
Myoglobin, CKMB mass, CK isoforms, cTnI, and cTnT have equivalent early sensitivities for detecting AMI within the first hours of chest pain, outperforming traditional CK and CKMB activity.
Mair et al. (1995) studied this question.
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