Population
Preclinical model of cardiac hypertrophy provoked by hemodynamic overload (aortic constriction/coarctation)
Design
Preclinical
Follow-up
up to 30 days
Authors
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May mark pressure-overload hypertrophy extent; hypothesis-generating in animal models, clinical translation untested.
Smooth muscle alpha-actin serves as a molecular marker for the presence and extent of pressure-overload cardiac hypertrophy.
Black et al. (1991) studied this question.
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