Why the study?
Does prostaglandin E1 infusion improve cardiocirculatory actions in patients with severe ischemic congestive cardiac failure?
Population
9 coronary patients with severe left ventricular (LV) failure (severe ischemic congestive cardiac failure)
Design
Case_series
Authors
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May support PGE1 in severe ischemic HF; hypothesis-generating and leaves open randomized confirmation.
Does prostaglandin E1 infusion improve cardiocirculatory actions in patients with severe ischemic congestive cardiac failure?
Prostaglandin E1 infusion acts as a potent arteriolar vasodilator, improving myocardial energetics and cardiac function in patients with severe ischemic heart failure.
Awan et al. (1981) studied this question.
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