Key result
HF is linked to worse memory, psychomotor speed, and cerebral grey matter loss versus controls.
Why the study?
It was unclear whether the cognitive dysfunction associated with heart failure is attributable to HF itself or comorbid conditions such as ischaemic heart disease.
Does systolic heart failure associate with cognitive impairment and cerebral grey matter loss compared to controls with and without ischaemic heart disease?
Cross-Sectional (n=155)
Does systolic heart failure associate with cognitive impairment and cerebral grey matter loss compared to controls with and without ischaemic heart disease?
Systolic heart failure is associated with worse memory, psychomotor speed, and regional cerebral grey matter loss compared to controls without ischaemic heart disease.
No takes yet. Share an insight, caveat, or question.
HF associated with cognitive deficits and grey matter loss beyond IHD; leaves open causal mechanisms and need for longitudinal confirmation.
Almeida et al. (2012) conducted a cross-sectional in Heart failure and ischaemic heart disease (n=155). Heart failure vs. Controls with and without IHD was evaluated on Cognitive impairment and cerebral grey matter (GM) loss. Adults with heart failure had worse immediate and long-term memory and psychomotor speed, and showed cerebral grey matter loss in multiple regions compared with controls without IHD.
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