Why the study?
Does heart failure lead to regional hippocampal volume reduction compared to healthy controls?
Population
17 heart failure patients and 34 healthy control subjects.
Design
Case-control
Authors
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HF-associated right hippocampal atrophy may underlie cognitive issues; leaves open causality and requires prospective validation.
Does heart failure lead to regional hippocampal volume reduction compared to healthy controls?
Heart failure is associated with regional hippocampal volume reduction, particularly in the CA1 area, which may contribute to the cognitive and mood impairments often seen in these patients.
Woo et al. (2015) studied this question.
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