What question did this study set out to answer?

To explore the correlation between left ventricular mass, blood pressure, and adipose tissue distribution in elderly obese individuals.

February 1, 1998European Heart JournalOpen Access

Hyperinsulinaemia, regional adipose tissue distribution and left ventricular mass in normotensive, elderly, obese subjects

Q: What does this research mean for the field?

Centripetal adipose tissue distribution and hyperinsulinaemia are closely correlated with increased left ventricular mass in normotensive elderly obese subjects, independent of blood pressure. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Why the study?

Is there a correlation between left ventricular mass, regional adipose tissue distribution, and hyperinsulinaemia in normotensive, elderly, obese subjects compared to lean subjects?

Population

49 elderly male subjects (29 obese, 20 lean), mean age 68.5 +/- 6.4 years.

Design

Cross-sectional

Authors

FVFrancesco VettaOspedale San Filippo Neri

Discussion

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Implication

Visceral fat and hyperinsulinaemia were associated with higher LV mass in elderly obese subjects; hypothesis-generating, prospective studies needed before clinical implications.

Key Points

To explore the correlation between left ventricular mass, blood pressure, and adipose tissue distribution in elderly obese individuals.
Selected two groups of elderly male subjects: 29 obese and 20 lean.
Evaluated left ventricular mass via echocardiography and blood pressure through ambulatory monitoring.
Used Student's t-test and linear regression for statistical analysis.
Increased left ventricular mass observed in obese subjects (P < 0.0001).
Higher insulin area under curve in obese vs lean subjects (P < 0.0001).
Strong correlation found between left ventricular mass and visceral adipose tissue (r = 0.607; P < 0.0001) and hyperinsulinaemia (r = 0.615; P < 0.0001).

Structured PICO

Is there a correlation between left ventricular mass, regional adipose tissue distribution, and hyperinsulinaemia in normotensive, elderly, obese subjects compared to lean subjects?

Population

49 elderly male subjects (29 obese, 20 lean), mean age 68.5 +/- 6.4 years.

Comparator

Lean subjects (n=20)

Outcome

Left ventricular mass evaluated echocardiographicallysurrogate

Centripetal adipose tissue distribution and hyperinsulinaemia are closely correlated with increased left ventricular mass in elderly obese men, independent of blood pressure.

Cite This Study

Francesco Vetta (1998) studied this question.

synapsesocial.com/papers/6a1db946c8f6dd20ef4db574 https://doi.org/10.1053/euhj.1997.0731

Topics

Echocardiography

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Implication

Visceral fat and hyperinsulinaemia were associated with higher LV mass in elderly obese subjects; hypothesis-generating, prospective studies needed before clinical implications.

Hyperinsulinaemia, regional adipose tissue distribution and left ventricular mass in normotensive, elderly, obese subjects

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Hyperinsulinaemia, regional adipose tissue distribution and left ventricular mass in normotensive, elderly, obese subjects

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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