Key result
Quitting smoking after acute myocardial infarction was associated with lower unadjusted 4-year mortality (17% vs 31%, p<0.05) compared to continued smoking, but not significant after adjustment.
Why the study?
Does quitting smoking reduce mortality in patients hospitalized with acute myocardial infarction?
Population
862 consecutive patients hospitalized in a single hospital due to acute myocardial infarction (AMI).
Comparison
Quitting smoking after surviving the first year… vs Continuing to smoke after surviving the first…
Design
Cohort
Follow-up
4 years (after the first year)
Authors
Loading...
Smoking cessation post-AMI shows no independent mortality benefit after adjustment; leaves open whether quitting improves survival and requires RCTs.
Cohort (n=862)
No
Does quitting smoking reduce mortality in patients hospitalized with acute myocardial infarction?
Absolute Event Rate: 17% vs 31%
p-value: p=< 0.05
The apparent survival benefit of quitting smoking after an AMI may be confounded by baseline differences, as quitters had fewer previous MIs and less congestive heart failure.
Herlitz et al. (2008) conducted a cohort in Acute myocardial infarction (n=862). Quitting smoking vs. Continued smoking was evaluated on Mortality during the subsequent 4 years (p=< 0.05). Quitting smoking after acute myocardial infarction was associated with lower unadjusted 4-year mortality (17% vs 31%, p<0.05) compared to continued smoking, but not significant after adjustment.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: