What question did this study set out to answer?

To quantify comb growth-promoting male hormones in human urine using a capon biological assay.

April 1, 1937Biochemical JournalOpen Access

Capon comb growth-promoting substances (“male-hormones”) in human urine of males and females of varying ages

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Authors

EDE DingemanseUniversity of Amsterdam HBHelene BorchardtUniversity of Amsterdam ELErnst LaqueurUniversity of Amsterdam

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Implication

Bioassay analysis reveals variable levels of comb growth-promoting substances in human urine, highlighting measurable androgenic biological activity across individuals.

Key Points

To quantify comb growth-promoting male hormones in human urine using a capon biological assay.
Extracted male hormone substances from human urine samples using benzene.
Administered fractions of the extract to capons over four consecutive days to measure comb surface area enlargement.
Comb growth-promoting hormone content in adult male urine ranged from less than 4 to more than 12 units per liter.
The average hormone concentration observed across tested male urine samples was 4 to 6 units per liter.

Cite This Study

Dingemanse et al. (1937) studied this question.

synapsesocial.com/papers/6a1dca95c169426e5434cb84 https://doi.org/10.1042/bj0310500

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Implication

Bioassay analysis reveals variable levels of comb growth-promoting substances in human urine, highlighting measurable androgenic biological activity across individuals.

Capon comb growth-promoting substances (“male-hormones”) in human urine of males and females of varying ages

Discussion

Member takes

Implication

Key Points

Cite This Study

Capon comb growth-promoting substances (“male-hormones”) in human urine of males and females of varying ages

Discussion

Member takes

Implication

Key Points

Cite This Study

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