What does this research mean for the field?

In patients with complete heart block and dual chamber pacemakers, an atrioventricular (AV) interval of 150 or 200 ms maximizes cardiac output at heart rates between 80 and 118 beats/minute, whereas an interval of 250 ms significantly decreases cardiac output. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

Determine the optimal atrioventricular interval to maximize cardiac output across different heart rates in patients with dual chamber pacemakers.

September 1, 1986Pacing and Clinical Electrophysiology

Optimum AV Interval in Dual Chamber Pacemakers

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Why the study?

Does adjustment of the AV interval maximize cardiac output in patients with complete heart block and dual chamber pacemakers?

Population

10 consecutive patients with complete heart block and dual chamber pacemakers

Comparison

Adjustment of atrioventricular intervals at… vs Different AV intervals and heart rates within…

Design

Case_series

Authors

RHRichard J. HaskellHoag Memorial Hospital Presbyterian WFWilliam J. FrenchInterventional Cardiology

Discussion

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Implication

AV optimization may enhance output in dual-chamber pacing for complete heart block; hypothesis-generating case data leaves prospective validation open.

Key Points

Determine the optimal atrioventricular interval to maximize cardiac output across different heart rates in patients with dual chamber pacemakers.
Evaluated 10 consecutive patients with complete heart block and implanted dual chamber pacemakers (N=10).
Paced patients at heart rates of 80, 100, and 118 beats/minute across five different atrioventricular intervals.
Measured simultaneous cardiac output noninvasively using pulsed Doppler ultrasound.
Maximum cardiac output occurred at atrioventricular intervals of 150 and 200 ms at heart rates of 80 and 100 beats/minute, and at 150 ms at 118 beats/minute (p < .05).
Increasing the atrioventricular interval to 250 ms resulted in a statistically significant decrease in cardiac output across all tested heart rates (p < .01).

Structured PICO

Does adjustment of the AV interval maximize cardiac output in patients with complete heart block and dual chamber pacemakers?

Population

10 consecutive patients with complete heart block and dual chamber pacemakers

Intervention

Adjustment of atrioventricular (AV) intervals (five different intervals) at paced heart rates of 80, 100, and 118 beats/minute

Comparator

Different AV intervals (including 250 ms) and heart rates within the same patients

Outcome

Cardiac output measured simultaneously using pulsed Dopplersurrogate

An AV interval of 150 or 200 ms provides the highest cardiac output in most patients with complete heart block and dual chamber pacemakers.

Cite This Study

Haskell et al. (1986) studied this question.

synapsesocial.com/papers/6a1df1885c054b78c2ef97cd https://doi.org/10.1111/j.1540-8159.1986.tb05414.x

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Implication

AV optimization may enhance output in dual-chamber pacing for complete heart block; hypothesis-generating case data leaves prospective validation open.

Optimum AV Interval in Dual Chamber Pacemakers

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Optimum AV Interval in Dual Chamber Pacemakers

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

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