Practical Considerations for Using Novel Oral Anticoagulants in Patients With Atrial Fibrillation
Why the study?
What are the practical considerations for using novel oral anticoagulants compared to vitamin K antagonists in patients with atrial fibrillation?
Population
Patients with atrial fibrillation
Comparison
Novel oral anticoagulants vs Warfarin or other vitamin K antagonists
Design
Review
Authors
Discussion
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Member takes
Implication
May inform NOAC selection and management in AF; leaves open need for prospective validation of strategies.
Structured PICO
What are the practical considerations for using novel oral anticoagulants compared to vitamin K antagonists in patients with atrial fibrillation?
P
Population
Patients with atrial fibrillation
I
Intervention
Novel oral anticoagulants (dabigatran, rivaroxaban, apixaban)
C
Comparator
Warfarin or other vitamin K antagonists
O
Outcome
Stroke prevention and practical management (patient selection, renal impairment, bleeding, drug interactions)
This review provides practical guidance on the clinical use of novel oral anticoagulants for stroke prevention in patients with atrial fibrillation.
Cite This Study
Savelieva et al. (2013) studied this question.