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This review examines the pharmacological properties, therapeutic applications, and cultural significance of Piper betle Linn.

June 2, 2026Open Access

Piper Betle Linn (Betel Leaf): A Comprehensive Review of Its Pharmacological Activities, Therapeutic Potential and Cultural Significance

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Systematic review evaluates pharmacological properties and cultural heritage of betel leaf, indicating its therapeutic potential.

This review examines the pharmacological properties, therapeutic applications, and cultural significance of Piper betle Linn.
Conducted a systematic review of existing literature on Piper betle Linn.
Analyzed bioactivities including antibacterial, antioxidant, anti-inflammatory, anticancer, antidiabetic, and neuroprotective effects.
Explored its applications in traditional medicine and cultural practices.
Piper betle Linn exhibits significant pharmacological activities such as antibacterial and antioxidant effects.
Key phytochemicals include flavonoids, phenolic compounds, alkaloids, and essential oils that contribute to its bioactivities.
Recognized as 'leaf of prosperity' with potential for integration into modern medical practice.

Dnyaneshwar Kisan Hule*, Vaishnavi Prabhakar Lamkhade, Rutuja Ganesh Kadlag, Samiksha Bhausaheb Kshirsagar (2026) studied this question.

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