Why the study?
Although metabolic syndrome is linked to incident CVD, whether specific combinations of its criteria confer higher risk than others remains unknown.
Do certain combinations of metabolic syndrome criteria confer a higher risk of incident cardiovascular disease than others?
Population
388,800 individuals in the UK Biobank with MetS data
Comparison
Different combinations and numbers of MetS criteria
Design
Prospective cohort study
Follow-up
Median of 12.6 years
Authors
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Specific MetS combinations may flag higher CVD risk; extends criterion-specific data but leaves clinical adoption open.
Do certain combinations of metabolic syndrome criteria confer a higher risk of incident cardiovascular disease than others?
Certain combinations of metabolic syndrome criteria, particularly those involving glucose, waist circumference, and HDL, are associated with a substantially higher risk of future cardiovascular disease.
Lars Lind (2023) studied this question.