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September 1, 1956Circulation Research36 citationsOpen Access

Effect of Hypothermia on Oxygen Consumption and Energy Utilization of Heart

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HBHenry S. BadeerAKAvedis K. Khachadurian

Structured PICO

P
Population
Denervated dog's heart doing constant work in a modified heart-lung preparation (HLP)
I
Intervention
Hypothermia (temperature between 36 and 26 C)
O
Outcome
Oxygen uptake and mechanical efficiencysurrogate

In a canine model, hypothermia increases the mechanical efficiency of the heart without impairing aerobic energy conversion.

Abstract

The oxygen uptake of the denervated dog's heart doing constant work in a modified HLP appears to vary logarithmically with temperature between 36 and 26 C. Under these conditions hypothermia increases the mechanical efficiency of the heart. It is concluded that cold does not interfere with the conversion of aerobic energy into useful work done by the myocardium.

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Cite This Study

Badeer et al. (1956) studied this question.

synapsesocial.com/papers/6a1e74a0c07483b92c55e5aehttps://doi.org/10.1161/01.res.4.5.523
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